REILLY ASSOCIATES
 
Capabilities


A research and consulting firm specializing in the design, implementation and analysis of quality of life and economic studies for pharmaceutical companies.  

Selects appropriate outcomes measures from the literature and /or develops and tests new measures tailored to specific research needs.

Has designed and conducted outcomes research for numerous diseases and patient / caregiver populations including:


Feagan BG, Reilly MC, Gerlier L, Brabant Y, Brown M, Schreiber S. Clinical
trial: the effects of certolizumab pegol therapy on work productivity in patients
with moderate-to-severe Crohn's disease in the PRECiSE 2 study. Aliment Pharmacol
Ther. 2010 Mar 18. [Epub ahead of print]

Reilly MC, Gooch KL, Wong RL, Kupper H, van der Heijde D,  Validity, reliability and responsiveness of the Work Productivity and Activity Impairment Questionnaire in ankylosing spondylitis . Rhuematology 2010; Jan 25. [Epub ahead of print].

Wahlqvist P, Medin J, Karlsson M, Reilly MC. Responsiveness to change and construct validity of the Work Productivity and Activity Impairment questionnaire for gastroesophageal reflux disease (WPAI:GERD) in Swedish patients.  Poster presentation, ISPOR 14th Annual International Meeting, Orlando, FL, May 16, 2009.

Reilly MC, Gerlier L, Brabant Y, Brown, M. Validity, reliability and responsiveness of the Work Productivity and Activity Impairment questionnaire in Crohn’s disease. Clin Ther. 2008; 30(2):393-404.

Reilly MC, Gerlier L, Brown M. Discriminant validity of the Work Productivity and Activity Impairment questionnaire in patient’s with Crohn’s disease. Value in Health. 2006; 9(6):A246. (Abstract.)

Reilly MC, Gerlier L, Brown M. Discriminant validity of the Work Productivity and Activity Impairment questionnaire in patient’s with Crohn’s disease. Presented ISPOR 9th Annual European Congress, 28-31 October 2006, Copenhagen, Denmark. 

Wahlqvist P, Reilly M, Barkun A. Systematic review: the impact of gastro-oesophageal reflux disease on work productivity. Alimentary Pharmacology & Therapeutics 2006:24(2):259-272.

Reilly MC, Relkin N, Zbrozek A. Development and testing of a new outcome measure of relationship between patients with Alheimer's disease and their partners.  Am J Alzheimer's Dis and Other Dementias.  2006; 21(4):249-257.

Feagan B, Schreiber S, Selke B, Reilly MC, Sanborn W.  Moderate to severe Crohn's disease induces high productivity losses: Work Productivity and Activity Impairment (WPAI) baseline data from the PRECiSE program.  Digestive Disease Week.  May 20-25, 2006, Los Angeles, CA.

Bushnell DM, Reilly MC, Galani C, Martin ML, Ricci JF, , Patrick DL, McBurney C.  Validation of EDC versions of IBS-QOL, EQ-5D and WPAI-IBS questionnaires. Value in Health. 2006; 9(2):65-140.

Gawlicki MC, Reilly MC, Popielnicki A, Reilly K.  Linguistic validation of the US Spanish Work Productivity and Activity Impairment questionnaire, general health version (WPAI:GH). Value in Health 2006; 9(3):199-204.

Wahlqvist P, Reilly M, Barkun A. The impact of gastroesophageal reflux disease on work productivity: a systematic review. Value in Health 2005;8(6):A122.

Wahlqvist P, Reilly M, Barkun A. The impact of gastroesophageal reflux disease on work productivity: a systematic review. Presented ISPOR 8th Annual European Conference, November  6-8, 2005, Florence Italy.

Reilly MC, McBurney CR, Bracco A.  Work absenteeism in irritable bowel syndrome (IBS): measuring days versus hours missed.  Presented ISPOR 8th Annual European Congress, Nov 6-8, 2005, Florence, Italy. 

Reilly MC, Bracco A McBurney CR.  IBS-C patients have greater treatment satisfaction with initial and repeated use of tegaserod.  Presented American College of Gastroenterology, October 28-Nov. 2, 2005, Honolulu, Hawaii.

Bracco A, Reilly MC, McBurney C, Ambegaonkar B. Burden of irritable bowel syndrome with constipation on health care resource utilisation, work productivity and activity impairment and quality of life in France, Germany and United Kingdom.  Presented United European Gastroenterology Week, Oct 15-19, 2005, Copenhagen, Denmark

Reilly MC, McBurney CR.  Responsiveness of the Work Productivity and Activity Impairment Questionnaire for Irritable Bowel Syndrome with Constipation (WPAI:IBS-C) to clinically meaningful change.  Presented American College of Gastroenterology October 30, 2005, Honolulu, Hawaii.

Reilly MC, McBurney CR, Bracco A. Responsiveness of the Work Productivity and Activity Impairment questionnaire for irritable bowel syndrome with constipation (WPAI:IBS-C) to clinically meaningful change. Am J Gastroenterol 2005; 100(9): S762. 

Reilly MC, Zbrozek AS.  Development and testing of a new outcome measure of relationship between patients with Alzheimer’s disease and their partners.  Presented 4th International Pharmacoeconomics Conference on Alzheimer’s Disease, Sept 24-25, 2005, Stockholm, Sweden.

Bracco A, Reilly MC, McBurney C, Ambegaonkar B.  Burden of Irritable Bowel Syndrome with constipation on health care resource utilization, work productivity and activity impairment and quality of life.  Presented 13th World Congress of Gastroenterology, September 10-14, 2005,  Montreal, Canada.

Reilly MC, Barghout V, McBurney CR.  Effect of tegaserod on work and daily activity: results from ZENSAA..  Presented 13th World Congress of Gastroenterology, September 10-14, 2005, Montreal, Canada.

Reilly MC, Barghout V, McBurney CR, Niecko TE.  Effect of tegaserod on work and daily activity in IBS with constipation.  Aliment Pharmacol & Ther 2005; 22:373-380. 

Gawlicki MC, Reilly MC, Popielnicki A, Reilly K.  Linguistic validation of the US Spanish Work Productivity and Activity Impairment questionnaire, general health version (WPAI:GH). Presented ISPOR Tenth Annual International Meeting, May 17, 2005, Washington, DC.

Bushnell DM, Galani C, Martin ML, Ricci JF, Reilly MC, Patrick DL.Validation of EDC versions of IBS-QOL, EQ-5D and WPAI-IBS questionnaires.Value in Health 2005 (8):383.

Reilly MC, Barghout V, Ruegg P, Pecher E, Ricci J-F.  Tegaserod significantly reduces work productivity loss and daily activity impairment in patients with IBS with constipation.  Am J Gastroenterol 2004;99(10):S241.

Reilly MC, Bracco A, Geissler K, Johanson J, Kahler KH.  Impact of irritable bowel syndrome (IBS) on work productivity and daily activities.  Presented 69th Annual Meeting American College of Gastroenterology,: Orlando FL, 3 Nov 2004.

Reilly MC, Bracco A, Ricci J-F, Santoro J, Stevens T.  The validity and accuracy of the Work Productivity and Activity Impairment questionnaire - irritable bowel syndrome version (WPAI:IBS).   Aliment  Pharmacol Ther 2004; 20:459-467.

Reilly MC, Lavin PT, Kahler KH, Pariser DM.  Validation of the Dermatology Life Quality Index (DLQI) and the Work Productivity and Activity Impairment: Chronic Hand Dermatitis Questionnaire (WPAI-ChHD) in Chronic Hand Dermatitis (ChHD).  J Am Academy Dermatol.2003;48:128-30.

Reilly M, Lavin P, Kahler K. Quality of life and work productivity analysis of patients with mild to moderate chronic hand dermatitis.  Presented American Academy of Dermatology, 60th Annual Meeting, Feb. 22-27, 2002.

Reilly M, Lavin P, Kahler K.  Effect of pimecrolimus cream 1% on quality of life and work productivity outcomes of patients with mild to moderate chronic hand dermatitis.  Presented American Academy of Dermatology, 60th Annual Meeting, Feb. 22-27, 2002.

Reilly M, Lavin P, Kahler K.  Validation of quality of life and work productivity instruments in patients with chronic hand dermatitis.  Presented American Academy of Dermatology, 60th Annual Meeting, Feb. 22-27, 2002.

Reilly MC, Tanner A, Meltzer EO.  Allergy impairment questionnaires: validation studies.  J Allergy Clin Immunology 1996;97:1:3:430.

Reilly MC, Tanner A, Meltzer EO. Work, classroom and activity impairment instruments: validation studies in allergic rhinitis.  Clinical Drug Investigations 1996; 11(5):278-288.  

Reilly MC, Zbrozek AS, Dukes EM.  The validity and reproducibility of a work productivity and activity impairment instrument.  PharmacoEconomics 1993; 4(5):353-65.

Reilly MC, Zbrozek AS: Assessing the responsiveness of a quality of life instrument and the measurement of symptom severity in essential hypertension.  PharmacoEconomics 1992;2(1): 1-13.
           
Reilly MC, Clark T: Methodological issues in assessing quality of life in patients with urinary incontinence: a preliminary report.  J Res Pharm Econ 1990; 2(4):3-15.

Reilly MC: Quality of life studies: Balancing the cost and quality.  Pharm Exec 1989; 9(12):50-54.

Stergachis A, Blissenbach HF, Bloom BS, Hillman AL, Klipper A, Reilly M, Trotter J: Determining the economic value of misoprostol for patients taking NSAIDS: a roundtable discussion.  Medical Interface(S), October, 1989.

Reilly MC: Quality of life moves beyond safety and efficacy.  Pharm Exec 1989; 9(9):58-64.
   
Reilly MC: Restriction of Medicaid funding of abortions.  New Eng J Med 1982; 13:3O7.

Reilly PC Jr., Reilly MC: The cost of outpatient physicians' services at a Veteran Administration hospital.  Annals of Int Med 1980; 93:128-132.

Palmer RH, Reilly MC: Individual and institutional variables which may serve as indicators of quality of medical care.  Med Care 1979; 17:693-717.

Reilly PC Jr., Reilly MC, Catino J, Catino D. High-risk travel and malaria. N Engl J Med. 1977; 296 (26): 1536.

President of Reilly Associates since 1989.

30 years of experience conducting survey research and outcomes research for leading pharmaceutical companies..  

M.P.H. Harvard University; M.A. University of Virginia.  

Previously  Director of Clinical Studies and Survey Research at Health Data Resources, Providence, Rhode Island.  Conducted statewide health surveys for the R.I Department of Health, health insurers, hospitals and health organizatizations.
Margaret Reilly, M.A., M.P.H.
Allergies
Angina
Arthritis
Alzheimer's disease
Benign Prostatic Hyperplasia 
Bronchitis
Cancer
Claudication
Crohn's disease
Congestive Heart Failure
Dermatological conditions
Diabetes
Hypertension
Irritable Bowel Syndrome
Urinary incontinence  
Renal disease
Publications and Presentations